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Cradle

Cradle is an AI platform for protein engineering. Ideal for biotech R&D teams, it helps design and optimize protein sequences using generative machine learning.

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November 11th, 2022

About Cradle

Cradle is an AI platform that helps biologists and research teams design and optimize protein sequences without the slow trial-and-error of traditional lab cycles.

The platform utilizes large language models (LLMs) trained on over 1 billion protein sequences to suggest modifications that improve stability, activity, and binding affinity. By leveraging multi-objective optimization, scientists can simultaneously refine disparate traits like thermal resistance and catalytic efficiency. Cradle typically reduces the number of experimental rounds from 10 down to just 3, providing a verified research speedup of up to 12x.

Unlike traditional biotech partnerships, Cradle operates on a pure software subscription model with a zero-royalty policy. This ensures that organizations retain 100% of the intellectual property generated through the platform. Data is hosted in secure, private workspaces that meet SOC 2 and ISO 27001 standards, ensuring customer sequences are never used to train models for competitors.

Browser / Automation – Web Interface Toolchain – REST API for lab hardware integration

How it works

  1. Sequence generation, property prediction, active learning

Capabilities – Enzyme engineering, antibody design, peptide optimization

Pricing

IP Policy

$0 Royalties

Users maintain 100% ownership of all generated intellectual property.

Academic Tier: Contact for Quote - Tailored for not-for-profit research institutions. Standard Plan: Contact for Quote - Annual license based on the number of active projects. Enterprise Plan: Contact for Quote - Custom scaling for large multi-division organizations.

Discover Cradle and thousands of other AI tools on Beyond The AI - your trusted directory for AI solutions.

Who is using Cradle?

Protein EngineersBiotech R&D TeamsPharmaceutical ResearchersEnzyme ChemistsSynthetic Biologists

Key Features

7 features
  • Generative Protein Design
  • Multi-Objective Optimization
  • Property Prediction Models
  • SOC 2 & ISO 27001 Compliance
  • API for Lab Automation
  • Private Data Workspaces
  • Interactive Sequence Visualization

Use Cases

4 use cases
  • Improving thermal stability of industrial enzymes
  • Optimizing antibody binding affinity
  • Developing novel peptides for therapeutics
  • Reducing lab cycle times in vaccine development
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